Chewing food 40 times instead of a typical 15 times caused study participants to eat nearly 12 percent fewer calories, according to results published in the American Journal of Clinical Nutrition. Jie Li and colleagues from Harbin Medical University in China gave a typical breakfast to 14 obese young men and 16 young men of normal weight to see if there were differences in how they chewed their food. The researchers also looked to see whether chewing more would lead subjects to eat less and would affect levels of blood sugar or certain hormones that regulate appetite. In the current study, the team found a connection between the amount of chewing and levels of several hormones that “tell the brain when to begin to eat and when to stop eating,” said co-author Shuran Wang in an email. The 12 percent reduction in calories eaten by the group who chewed their food 40 times in the study could potentially translate into significant weight loss (nearly 25 pounds in one year, said Adam Drewnowski, director of the University of Washington Center for Obesity Research in Seattle).